AustralieFrV1, Main, Exploration, bibRecord, 00A462

Role of modifiable risk factors in life expectancy in the elderly. Commentary

Identifieur interne : 00A462 ( Main/Exploration ); précédent : 00A461; suivant : 00A463

Role of modifiable risk factors in life expectancy in the elderly. Commentary

Auteurs : Bruce Neal [Australie] ; Athanase Benetos [France] ; Frédérique Thomas [France] ; Kathryn E. Bean [France] ; Bruno Pannier [France] ; Louis Guize [France]

Source :

Journal of hypertension [ 0263-6352 ] ; 2005.

RBID : Pascal:05-0455086

Descripteurs français

Pascal (Inist)
- Appareil circulatoire pathologie, Hypertension artérielle, Facteur risque, Personne âgée.
Wicri :
- topic : Personne âgée.

English descriptors

KwdEn :
- Cardiovascular disease, Elderly, Hypertension, Risk factor.

Abstract

Objective The aim of the present study was to evaluate the role of 'modifiable' risk factors, assessed between the ages of 60 and 70 years, in late survival. Design The study population included subjects aged 60-70 years, who had a standard health examination at the IPC Center, and who could potentially reach the age of 80 years for men and 85 years for women at the end of the follow-up period. Methods The role of 'modifiable' risk factors was assessed by comparing subjects who died before the age of 80 years for men (n = 1333) and before 85 years for women (n = 543) to subjects who survived beyond these ages (3681 men, 1910 women). Multivariate analyses were conducted to determine which parameters were independently associated with survival to an advanced age. Results The multivariate analysis showed a decreased probability of late survival with higher pulse pressure (P< 0.0001), higher heart rate (P< 0.002), higher glycemia (P< 0.0034), and an increased probability with regular physical activity (P< 0.0001). A significant interaction between heart rate and gender (P<0.01) was observed, indicating that heart rate was a predictor of late survival in men but not in women. Body mass index, cholesterol and triglyceride levels, and diastolic blood pressure and tobacco smoking were not associated with late survival in this population. Conclusions A systematic search for certain risk factors in an elderly patient can have a significant impact on late survival and can lead to the establishment of priority goals, such as increasing physical activity and reducing blood pressure, heart rate and glycemia.

Affiliations:

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Objective The aim of the present study was to evaluate the role of 'modifiable' risk factors, assessed between the ages of 60 and 70 years, in late survival. Design The study population included subjects aged 60-70 years, who had a standard health examination at the IPC Center, and who could potentially reach the age of 80 years for men and 85 years for women at the end of the follow-up period. Methods The role of 'modifiable' risk factors was assessed by comparing subjects who died before the age of 80 years for men (n = 1333) and before 85 years for women (n = 543) to subjects who survived beyond these ages (3681 men, 1910 women). Multivariate analyses were conducted to determine which parameters were independently associated with survival to an advanced age. Results The multivariate analysis showed a decreased probability of late survival with higher pulse pressure (P< 0.0001), higher heart rate (P< 0.002), higher glycemia (P< 0.0034), and an increased probability with regular physical activity (P< 0.0001). A significant interaction between heart rate and gender (P<0.01) was observed, indicating that heart rate was a predictor of late survival in men but not in women. Body mass index, cholesterol and triglyceride levels, and diastolic blood pressure and tobacco smoking were not associated with late survival in this population. Conclusions A systematic search for certain risk factors in an elderly patient can have a significant impact on late survival and can lead to the establishment of priority goals, such as increasing physical activity and reducing blood pressure, heart rate and glycemia.</div>
</front>
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<tree><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Neal, Bruce" sort="Neal, Bruce" uniqKey="Neal B" first="Bruce" last="Neal">Bruce Neal</name>
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<country name="France"><region name="Île-de-France"><name sortKey="Benetos, Athanase" sort="Benetos, Athanase" uniqKey="Benetos A" first="Athanase" last="Benetos">Athanase Benetos</name>
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<name sortKey="Bean, Kathryn E" sort="Bean, Kathryn E" uniqKey="Bean K" first="Kathryn E." last="Bean">Kathryn E. Bean</name>
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<name sortKey="Guize, Louis" sort="Guize, Louis" uniqKey="Guize L" first="Louis" last="Guize">Louis Guize</name>
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<name sortKey="Thomas, Frederique" sort="Thomas, Frederique" uniqKey="Thomas F" first="Frédérique" last="Thomas">Frédérique Thomas</name>
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Role of modifiable risk factors in life expectancy in the elderly. Commentary

Role of modifiable risk factors in life expectancy in the elderly. Commentary

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri